Protein structure of the month
Rigaku customers are the most productive in the world. Every month hundreds of protein crystal data sets are collected by scientists using Rigaku instruments. We are always pleased when we see our customers being productive with our equipment, so we have created this showcase for structures that have been released by the Protein Data Bank (PDB).
Every month we will select one recently released structure from the PDB that was solved from data collected with Rigaku instruments, and invite the Rigaku user to write up a short description of the structure for presentation on our web site.
Please explore the structures below to get a glimpse into the type of research and protein structures that are being studied by Rigaku users around the world.
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- October 2009
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Protein:
Cytoplasmic Domain of the Inner Membrane Protein EpsF, PDB ID: 2VMB
de novo Phasing at Home Using the Anomalous Signal of Iodide: The Structure Solution of Cytoplasmic Domain of the Inner Membrane Protein EpsFPerformed in the laboratory of Wim Hol, Department of Biochemistry, Biomolecular Structure Center, University of Washington, Seattle, WA.
»» Read more -
- September 2009
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Protein:
Mycobacterium tuberculosis KasA, PDB ID:
2WGD
Crystal structures of Mycobacterium tuberculosis KasA, a drug target involved in fatty acid biosynthesisPerformed in the laboratory of Caroline Kisker at the Rudolf Virchow Center for Experimental Biomedicine, Institute for Structural Biology, University of Würzburg, Würzburg, Germany.
»» Read more -
- July 2009
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Protein:
Filamin B, PDB ID: 2WAS
The consequences of disease-associated mutations on the structure and function of the filamin B actin binding domainPerformed in the laboratory of Andrew Sutherland-Smith in the Institute of Molecular BioSciences at Massey University Palmerston North, New Zealand.
»» Read more -
- June 2009
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Protein
1: ATP binary
complex, PDB ID: 3G59
Protein 2: substrate ternary complex, PDB ID: 3G5A
Structure and Mechanism of a Eukaryotic FMN AdenylyltransferasePerformed in the laboratory of Hong Zhang at the University of Texas Southwestern Medical Center, Dallas, TX.
»» Read more -
- May 2009
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Protein: human LGP2, PDB ID: 3EQT
The
RIG-I like Receptor LGP2 Recognizes the Termini of Double-stranded RNAPerformed in the laboratory of Pingwei Li, in the Department of Biochemistry and Biophysics at Texas A&M University.
»» Read more -
- April 2009
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Protein: Gluconate 5-dehydrogenase, PDB ID: 3CXR
Structural
basis of the catalytic mechanism of gluconate 5-dehydrogenase from Streptococcus
suisPerformed in the Laboratory of Prof. George F. Gao in the CAS Key Laboratory of Pathogenic Microbiology and Immunology (CASPMI), Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, P.R. China.
»» Read more -
- March 2009
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Protein: Mycoplasma hyorhinis protein, PDB ID: 3E78
Structure
determination of the cancer-associated Mycoplasma hyorhinis protein
Mh-p37Performed in the laboratory of Robert McKenna at the Center for Structural Biology, University of Florida.
»» Read more -
- February 2009
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Protein: Fructose-bisphosphate aldolase, PDB ID: 3EKZ
Structural basis for catalysis of a tetrameric,
class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosisPerformed in the laboratory of Andrew D Mesecar at the Center for Pharmaceutical Biotechnology, University of Illinois at Chicago.
»» Read more -
- December 2008
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Protein: κI O18/O8 N34I/Y87H, PDB
ID: 3CDC
Structural insights into the role of mutations in amyloidogenesisPerformed in the laboratory of Dr. Marina Ramirez-Alvarado in collaboration with Dr. James R. Thompson at the College of Medicine, Mayo Clinic..
»» Read more -
November
2008
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Protein: Human prostaglandin reductase, PDB ID: 2ZB7
Crystal structure of a human prostaglandin reductase in complex with NADPH and nicotinamidePerformed in the laboratory of Dr. Andrew H.-J. Wang at the Academia Sinica.
»» Read more -
- September 2008
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Protein: TetR/[Co Tc]+ complex, PDB
ID: 2vke
Anomalous diffraction used to confirm the metal ion in Tet repressor-tetracycline complexesPerformed in the laboratory of Dr. Winfried Hinrichs at the University of Greifswald.
»» Read more - August 2008
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Protein
1: ALIXBro1-CHMP4B complex, PDB ID: 3c3q
Protein 2: ALIXBro1-CHMP4C complex, PDB ID: 3c3r
ALIX-CHMP4 interactions in the human ESCRT pathwayPerformed in the laboratories of Dr. Wesley Sundquist and Dr. Christopher Hill at the University of Utah School of Medicine.
»» Read more
If you have a structure you would like to nominate for future months, please send us an email at info@rigaku.com.